What do you think will happen to them? I'm not being snarky; I genuinely don't know.
I think for many, when the rubber meets the road they (anti vaxxers, vaccine hesitant) will roll up their sleeves and get the shot. For those with 20yrs, they can put in for retirement, all others tough luck.
I've been told we have multiple O's and E's in our unit that have stated they are done if the vaccine is mandated, guess we'll see which ones were serious. It was even suggested for those that aren't near retirement and are against the mandate, consider leaving the reserves and reaffiliate once this "blows over" (personally, I don't think it will "blow over" and the vaccine(s) are here to stay.)