I just picked up an '06 GSXR 750 this weekend. I started out on a kawasaki 636r sportbike, then a Harley Sportster. I've yet to go down (knock on wood), but if I had to do it over again I would have gone with a less powerful first bike. More because it would be more fun starting out rather than having to ride around constantly paranoid of killing yourself.
True. What always made me cringe were the guys who would buy a new first bike.. and the next day talk about picking up knee pucks and heading to the hills. Crazy.