I would love to see a chart somewhere on the added manpower (broken down by officer, warrant, enlisted, civilian, contractor, as well as by designator/rating) that would be required to operate a 350-ship fleet. I imagine plussing up to 350 ships would merit a huge push for new accessions across the board - but I'd guess the increases would be lopsided... Notional: maybe we'd need far more SWOs than other URL designators.
Old school, next generation, deep space nine, or voyager?this is about as relevant as debating the ideal size of Starfleet, and about as likely to happen.